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RNA-seq of 272 gliomas revealed a novel, recurrent PTPRZ1-MET fusion transcript in secondary glioblastomas

Studies of gene rearrangements and the consequent oncogenic fusion proteins have laid the foundation for targeted cancer therapy. To identify oncogenic fusions associated with glioma progression, we catalogued fusion transcripts by RNA-seq of 272 gliomas. Fusion transcripts were more frequently foun...

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Detalles Bibliográficos
Autores principales: Bao, Zhao-Shi, Chen, Hui-Min, Yang, Ming-Yu, Zhang, Chuan-Bao, Yu, Kai, Ye, Wan-Lu, Hu, Bo-Qiang, Yan, Wei, Zhang, Wei, Akers, Johnny, Ramakrishnan, Valya, Li, Jie, Carter, Bob, Liu, Yan-Wei, Hu, Hui-Min, Wang, Zheng, Li, Ming-Yang, Yao, Kun, Qiu, Xiao-Guang, Kang, Chun-Sheng, You, Yong-Ping, Fan, Xiao-Long, Song, Wei Sonya, Li, Rui-Qiang, Su, Xiao-Dong, Chen, Clark C., Jiang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216918/
https://www.ncbi.nlm.nih.gov/pubmed/25135958
http://dx.doi.org/10.1101/gr.165126.113