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Widespread intron retention in mammals functionally tunes transcriptomes

Alternative splicing (AS) of precursor RNAs is responsible for greatly expanding the regulatory and functional capacity of eukaryotic genomes. Of the different classes of AS, intron retention (IR) is the least well understood. In plants and unicellular eukaryotes, IR is the most common form of AS, w...

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Detalles Bibliográficos
Autores principales: Braunschweig, Ulrich, Barbosa-Morais, Nuno L., Pan, Qun, Nachman, Emil N., Alipanahi, Babak, Gonatopoulos-Pournatzis, Thomas, Frey, Brendan, Irimia, Manuel, Blencowe, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216919/
https://www.ncbi.nlm.nih.gov/pubmed/25258385
http://dx.doi.org/10.1101/gr.177790.114