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High-resolution mapping of transcriptional dynamics across tissue development reveals a stable mRNA–tRNA interface

The genetic code is an abstraction of how mRNA codons and tRNA anticodons molecularly interact during protein synthesis; the stability and regulation of this interaction remains largely unexplored. Here, we characterized the expression of mRNA and tRNA genes quantitatively at multiple time points in...

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Detalles Bibliográficos
Autores principales: Schmitt, Bianca M., Rudolph, Konrad L.M., Karagianni, Panagiota, Fonseca, Nuno A., White, Robert J., Talianidis, Iannis, Odom, Duncan T., Marioni, John C., Kutter, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216921/
https://www.ncbi.nlm.nih.gov/pubmed/25122613
http://dx.doi.org/10.1101/gr.176784.114