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Linking signaling pathways to transcriptional programs in breast cancer

Cancer cells acquire genetic and epigenetic alterations that often lead to dysregulation of oncogenic signal transduction pathways, which in turn alters downstream transcriptional programs. Numerous methods attempt to deduce aberrant signaling pathways in tumors from mRNA data alone, but these pathw...

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Detalles Bibliográficos
Autores principales: Osmanbeyoglu, Hatice U., Pelossof, Raphael, Bromberg, Jacqueline F., Leslie, Christina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216927/
https://www.ncbi.nlm.nih.gov/pubmed/25183703
http://dx.doi.org/10.1101/gr.173039.114