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Cardiotoxic Changes of Colchicine Intoxication in Rats: Electrocardiographic, Histopathological and Blood Chemical Analysis

The microtubule inhibitor colchicine is cardiotoxic and is suggested to impair impulse formation and conduction. However, little is known about the electrocardiographic (ECG) changes induced by colchicine in experimental animals and the detailed pathogenesis of its cardiotoxicity. Therefore, we anal...

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Detalles Bibliográficos
Autores principales: Tochinai, Ryota, Suzuki, Katsuya, Nagata, Yuriko, Ando, Minoru, Hata, Chie, Komatsu, Kayoko, Suzuki, Tomo, Uchida, Kazumi, Kado, Shoichi, Kaneko, Kimiyuki, Kuwahara, Masayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217234/
https://www.ncbi.nlm.nih.gov/pubmed/25378807
http://dx.doi.org/10.1293/tox.2014-0013