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Effects of Repeated Intravenous Administration of Dextrans,Water-soluble Macromolecules, in Rats

We investigated the influence of repeated intravenous administration of dextrans (DEXs) to rats. Seven-week-old Sprague Dawley rats (6 males/group) were given intravenously 10% saline solutions of dextrans (DEXs), 40 kDa or 200–300 kDa, at a dose level of 5 mL/kg/day for 28 days and they were examin...

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Detalles Bibliográficos
Autores principales: Kitazawa, Ikue, Ito, Shino, Kagawa, Yusuke, Suehiro-Narita, Miki, Hashizume, Naoto, Minamisawa, Yuka, Nii, Aisuke, Kawakami, Akio, Nakajima, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217235/
https://www.ncbi.nlm.nih.gov/pubmed/25378808
http://dx.doi.org/10.1293/tox.2013-0067