Release of GLP-1 and PYY in response to the activation of G protein-coupled bile acid receptor TGR5 is mediated by Epac/PLC-ε pathway and modulated by endogenous H(2)S

Activation of plasma membrane TGR5 receptors in enteroendocrine cells by bile acids is known to regulate gastrointestinal secretion and motility and glucose homeostasis. The endocrine functions of the gut are modulated by microenvironment of the distal gut predominantly by sulfur-reducing bacteria o...

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Detalles Bibliográficos
Autores principales: Bala, Vanitha, Rajagopal, Senthilkumar, Kumar, Divya P., Nalli, Ancy D., Mahavadi, Sunila, Sanyal, Arun J., Grider, John R., Murthy, Karnam S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217307/
https://www.ncbi.nlm.nih.gov/pubmed/25404917
http://dx.doi.org/10.3389/fphys.2014.00420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217307/
https://www.ncbi.nlm.nih.gov/pubmed/25404917
http://dx.doi.org/10.3389/fphys.2014.00420

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