MCM Paradox: Abundance of Eukaryotic Replicative Helicases and Genomic Integrity

As a crucial component of DNA replication licensing system, minichromosome maintenance (MCM) 2–7 complex acts as the eukaryotic DNA replicative helicase. The six related MCM proteins form a heterohexamer and bind with ORC, CDC6, and Cdt1 to form the prereplication complex. Although the MCMs are well...

Descripción completa

Detalles Bibliográficos
Autores principales: Das, Mitali, Singh, Sunita, Pradhan, Satyajit, Narayan, Gopeshwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217321/
https://www.ncbi.nlm.nih.gov/pubmed/25386362
http://dx.doi.org/10.1155/2014/574850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217321/
https://www.ncbi.nlm.nih.gov/pubmed/25386362
http://dx.doi.org/10.1155/2014/574850

Ejemplares similares