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MCM Paradox: Abundance of Eukaryotic Replicative Helicases and Genomic Integrity

As a crucial component of DNA replication licensing system, minichromosome maintenance (MCM) 2–7 complex acts as the eukaryotic DNA replicative helicase. The six related MCM proteins form a heterohexamer and bind with ORC, CDC6, and Cdt1 to form the prereplication complex. Although the MCMs are well...

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Detalles Bibliográficos
Autores principales:	Das, Mitali, Singh, Sunita, Pradhan, Satyajit, Narayan, Gopeshwar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217321/ https://www.ncbi.nlm.nih.gov/pubmed/25386362 http://dx.doi.org/10.1155/2014/574850

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