Blocking αVβ3 Integrin Ligand Occupancy Inhibits the Progression of Albuminuria in Diabetic Rats

This study determined if blocking ligand occupancy of the αVβ3 integrin could inhibit the pathophysiologic changes that occur in the early stages of diabetic nephropathy (DN). Diabetic rats were treated with either vehicle or a monoclonal antibody that binds the β3 subunit of the αVβ3 integrin. Afte...

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Detalles Bibliográficos
Autores principales: Maile, Laura A., Gollahon, Katherine, Wai, Christine, Dunbar, Paul, Busby, Walker, Clemmons, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217341/
https://www.ncbi.nlm.nih.gov/pubmed/25389530
http://dx.doi.org/10.1155/2014/421827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217341/
https://www.ncbi.nlm.nih.gov/pubmed/25389530
http://dx.doi.org/10.1155/2014/421827

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