Oxidative metabolism of astrocytes is not reduced in hepatic encephalopathy: a PET study with [(11)C]acetate in humans

In patients with impaired liver function and hepatic encephalopathy (HE), consistent elevations of blood ammonia concentration suggest a crucial role in the pathogenesis of HE. Ammonia and acetate are metabolized in brain both primarily in astrocytes. Here, we used dynamic [(11)C]acetate PET of the...

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Detalles Bibliográficos
Autores principales: Iversen, Peter, Mouridsen, Kim, Hansen, Mikkel B., Jensen, Svend B., Sørensen, Michael, Bak, Lasse K., Waagepetersen, Helle S., Schousboe, Arne, Ott, Peter, Vilstrup, Hendrik, Keiding, Susanne, Gjedde, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217371/
https://www.ncbi.nlm.nih.gov/pubmed/25404890
http://dx.doi.org/10.3389/fnins.2014.00353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217371/
https://www.ncbi.nlm.nih.gov/pubmed/25404890
http://dx.doi.org/10.3389/fnins.2014.00353

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