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Molecular Chaperone Dysfunction in Neurodegenerative Diseases and Effects of Curcumin
The intra- and extracellular accumulation of misfolded and aggregated amyloid proteins is a common feature in several neurodegenerative diseases, which is thought to play a major role in disease severity and progression. The principal machineries maintaining proteostasis are the ubiquitin proteasoma...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217372/ https://www.ncbi.nlm.nih.gov/pubmed/25386560 http://dx.doi.org/10.1155/2014/495091 |