Atypical “seizure-like” activity in cortical reverberating networks in vitro can be caused by LPS-induced inflammation: a multi-electrode array study from a hundred neurons

We show here that a mild sterile inflammation induced by the endotoxin lipopolysaccharide (LPS), in a neuron/astrocyte/microglial cortical network, modulates neuronal excitability and can initiate long-duration burst events resembling epileptiform seizures, a recognized feature of various central ne...

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Detalles Bibliográficos
Autores principales: Gullo, Francesca, Amadeo, Alida, Donvito, Giulia, Lecchi, Marzia, Costa, Barbara, Constanti, Andrew, Wanke, Enzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217498/
https://www.ncbi.nlm.nih.gov/pubmed/25404893
http://dx.doi.org/10.3389/fncel.2014.00361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217498/
https://www.ncbi.nlm.nih.gov/pubmed/25404893
http://dx.doi.org/10.3389/fncel.2014.00361

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