Cargando…
Nucleosomal occupancy changes locally over key regulatory regions during cell differentiation and reprogramming
Chromatin structure determines DNA accessibility. We compare nucleosome occupancy in mouse and human embryonic stem cells (ESCs), induced-pluripotent stem cells (iPSCs) and differentiated cell types using MNase-seq. To address variability inherent in this technique, we developed a bioinformatic appr...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217530/ https://www.ncbi.nlm.nih.gov/pubmed/25158628 http://dx.doi.org/10.1038/ncomms5719 |