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Patterns of linkage disequilibrium and haplotype distribution in disease candidate genes
BACKGROUND: The adequacy of association studies for complex diseases depends critically on the existence of linkage disequilibrium (LD) between functional alleles and surrounding SNP markers. RESULTS: We examined the patterns of LD and haplotype distribution in eight candidate genes for osteoporosis...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC421754/ https://www.ncbi.nlm.nih.gov/pubmed/15157284 http://dx.doi.org/10.1186/1471-2156-5-11 |