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Myeloid suppressor cells require membrane TNFR2 expression for suppressive activity

TNF and TNF receptor type 2 (TNFR2) have been shown to be important for generation of myeloid-derived suppressor cells (MDSC). In order to analyze whether and how TNFR2 passes the effect of TNF on, myeloid cells from TNFR2-deficient mice were compared to respective cells from wild-type mice. Primary...

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Detalles Bibliográficos
Autores principales: Polz, Johannes, Remke, Annika, Weber, Sabine, Schmidt, Dominic, Weber-Steffens, Dorothea, Pietryga-Krieger, Anne, Müller, Nils, Ritter, Uwe, Mostböck, Sven, Männel, Daniela N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217546/
https://www.ncbi.nlm.nih.gov/pubmed/25400932
http://dx.doi.org/10.1002/iid3.19