Mitochondrial Channel Opener Diazoxide Attenuates Hypoxia-Induced sFlt-1 Release in Human Choriocarcinoma Cells

OBJECTIVES: To examine the effect of diazoxide on hypoxia-induced soluble fms-like tyrosin kinase-1 (sFlt-1) release in JEG-3 choriocarcinoma cells. METHODS: Cells were cultured under normoxia (20% O(2)) or hypoxia (1% O(2)), and expression of sFlt-1 mRNA and protein release was determined by quanti...

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Detalles Bibliográficos
Autores principales: Shin, Byeong Seop, Kim, Hwi Gon, Choi, Ook Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Menopause 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217563/
https://www.ncbi.nlm.nih.gov/pubmed/25371888
http://dx.doi.org/10.6118/jmm.2014.20.1.21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217563/
https://www.ncbi.nlm.nih.gov/pubmed/25371888
http://dx.doi.org/10.6118/jmm.2014.20.1.21

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