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Mitochondrial Channel Opener Diazoxide Attenuates Hypoxia-Induced sFlt-1 Release in Human Choriocarcinoma Cells
OBJECTIVES: To examine the effect of diazoxide on hypoxia-induced soluble fms-like tyrosin kinase-1 (sFlt-1) release in JEG-3 choriocarcinoma cells. METHODS: Cells were cultured under normoxia (20% O(2)) or hypoxia (1% O(2)), and expression of sFlt-1 mRNA and protein release was determined by quanti...
Autores principales: | Shin, Byeong Seop, Kim, Hwi Gon, Choi, Ook Hwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Menopause
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217563/ https://www.ncbi.nlm.nih.gov/pubmed/25371888 http://dx.doi.org/10.6118/jmm.2014.20.1.21 |
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