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c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry-related pockets

The ydaO riboswitch, involved in sporulation, osmotic stress responses and cell wall metabolism, targets the second messenger c-di-AMP with subnanomolar affinity. We have solved the structure of c-di-AMP bound to the Thermoanaerobacter tengcongenesis ydaO riboswitch, thereby identifying a five-helic...

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Detalles Bibliográficos
Autores principales: Ren, Aiming, Patel, Dinshaw J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217635/
https://www.ncbi.nlm.nih.gov/pubmed/25086509
http://dx.doi.org/10.1038/nchembio.1606