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c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry-related pockets
The ydaO riboswitch, involved in sporulation, osmotic stress responses and cell wall metabolism, targets the second messenger c-di-AMP with subnanomolar affinity. We have solved the structure of c-di-AMP bound to the Thermoanaerobacter tengcongenesis ydaO riboswitch, thereby identifying a five-helic...
Autores principales: | Ren, Aiming, Patel, Dinshaw J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217635/ https://www.ncbi.nlm.nih.gov/pubmed/25086509 http://dx.doi.org/10.1038/nchembio.1606 |
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