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Study familial hypertrophic cardiomyopathy using patient-specific induced pluripotent stem cells

AIMS: Familial hypertrophic cardiomyopathy (HCM) is one the most common heart disorders, with gene mutations in the cardiac sarcomere. Studying HCM with patient-specific induced pluripotent stem-cell (iPSC)-derived cardiomyocytes (CMs) would benefit the understanding of HCM mechanism, as well as the...

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Detalles Bibliográficos
Autores principales: Han, Lu, Li, Yang, Tchao, Jason, Kaplan, Aaron D., Lin, Bo, Li, You, Mich-Basso, Jocelyn, Lis, Agnieszka, Hassan, Narmeen, London, Barry, Bett, Glenna C.L., Tobita, Kimimasa, Rasmusson, Randall L., Yang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217687/
https://www.ncbi.nlm.nih.gov/pubmed/25209314
http://dx.doi.org/10.1093/cvr/cvu205