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(64)Cu-DOTA-Anti-CTLA-4 mAb Enabled PET Visualization of CTLA-4 on the T-Cell Infiltrating Tumor Tissues

Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) targeted therapy by anti-CTLA-4 monoclonal antibody (mAb) is highly effective in cancer patients. However, it is extremely expensive and potentially produces autoimmune-related adverse effects. Therefore, the development of a method to evaluate CT...

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Detalles Bibliográficos
Autores principales: Higashikawa, Kei, Yagi, Katsuharu, Watanabe, Keiko, Kamino, Shinichiro, Ueda, Masashi, Hiromura, Makoto, Enomoto, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217715/
https://www.ncbi.nlm.nih.gov/pubmed/25365349
http://dx.doi.org/10.1371/journal.pone.0109866