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The NOD2 p.Leu1007fsX1008 Mutation (rs2066847) Is a Stronger Predictor of the Clinical Course of Crohn's Disease than the FOXO3A Intron Variant rs12212067

BACKGROUND: Very recently, a sub-analysis of genome-wide association scans revealed that the non-coding single nucleotide polymorphism (SNP) rs12212067 in the FOXO3A gene is associated with a milder course of Crohn's disease (CD) (Cell 2013;155:57–69). The aim of our study was to evaluate the c...

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Detalles Bibliográficos
Autores principales: Schnitzler, Fabian, Friedrich, Matthias, Wolf, Christiane, Angelberger, Marianne, Diegelmann, Julia, Olszak, Torsten, Beigel, Florian, Tillack, Cornelia, Stallhofer, Johannes, Göke, Burkhard, Glas, Jürgen, Lohse, Peter, Brand, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217717/
https://www.ncbi.nlm.nih.gov/pubmed/25365249
http://dx.doi.org/10.1371/journal.pone.0108503