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Sclerotium rolfsii Lectin Induces Stronger Inhibition of Proliferation in Human Breast Cancer Cells than Normal Human Mammary Epithelial Cells by Induction of Cell Apoptosis

Sclerotium rolfsii lectin (SRL) isolated from the phytopathogenic fungus Sclerotium rolfsii has exquisite binding specificity towards O-linked, Thomsen-Freidenreich (Galβ1-3GalNAcα1-Ser/Thr, TF) associated glycans. This study investigated the influence of SRL on proliferation of human breast cancer...

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Detalles Bibliográficos
Autores principales: Savanur, Mohammed Azharuddin, Eligar, Sachin M., Pujari, Radha, Chen, Chen, Mahajan, Pravin, Borges, Anita, Shastry, Padma, Ingle, Arvind., Kalraiya, Rajiv D., Swamy, Bale M., Rhodes, Jonathan M., Yu, Lu-Gang, Inamdar, Shashikala R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217719/
https://www.ncbi.nlm.nih.gov/pubmed/25364905
http://dx.doi.org/10.1371/journal.pone.0110107