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Dopaminergic Neurotoxicants Cause Biphasic Inhibition of Purinergic Calcium Signaling in Astrocytes

Dopaminergic nuclei in the basal ganglia are highly sensitive to damage from oxidative stress, inflammation, and environmental neurotoxins. Disruption of adenosine triphosphate (ATP)-dependent calcium (Ca(2+)) transients in astrocytes may represent an important target of such stressors that contribu...

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Detalles Bibliográficos
Autores principales: Streifel, Karin M., Gonzales, Albert L., De Miranda, Briana, Mouneimne, Rola, Earley, Scott, Tjalkens, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217743/
https://www.ncbi.nlm.nih.gov/pubmed/25365260
http://dx.doi.org/10.1371/journal.pone.0110996