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Dopaminergic Neurotoxicants Cause Biphasic Inhibition of Purinergic Calcium Signaling in Astrocytes
Dopaminergic nuclei in the basal ganglia are highly sensitive to damage from oxidative stress, inflammation, and environmental neurotoxins. Disruption of adenosine triphosphate (ATP)-dependent calcium (Ca(2+)) transients in astrocytes may represent an important target of such stressors that contribu...
Autores principales: | Streifel, Karin M., Gonzales, Albert L., De Miranda, Briana, Mouneimne, Rola, Earley, Scott, Tjalkens, Ronald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217743/ https://www.ncbi.nlm.nih.gov/pubmed/25365260 http://dx.doi.org/10.1371/journal.pone.0110996 |
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