Surface Levels of CD20 Determine Anti-CD20 Antibodies Mediated Cell Death In Vitro

BACKGROUND: The sensitivity of human Burkitt's lymphoma cells to rituximab (Rtx) and tositumomab (Tst) was assessed on cells expressing different levels of CD20 on surface. Cells that harbor low CD20 levels may resists against therapeutics response to CD20-specific antibodies. We postulated tha...

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Detalles Bibliográficos
Autores principales: Singh, Vijay, Gupta, Damodar, Arora, Rajesh, Tripathi, Rajendra Prashad, Almasan, Alexandru, Macklis, Roger M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217761/
https://www.ncbi.nlm.nih.gov/pubmed/25364827
http://dx.doi.org/10.1371/journal.pone.0111113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217761/
https://www.ncbi.nlm.nih.gov/pubmed/25364827
http://dx.doi.org/10.1371/journal.pone.0111113

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