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Dihydroartemisinin inhibits vascular endothelial growth factor-induced endothelial cell migration by a p38 mitogen-activated protein kinase-independent pathway

Dihydroartemisinin (DHA), a semi-synthetic derivative of artemisinin, has been demonstrated to possess a strong antiangiogenic activity. However, the molecular mechanisms underlying this effect remain unclear. Endothelial cell (EC) migration is an essential component of angiogenesis, and the p38 mit...

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Detalles Bibliográficos
Autores principales: GUO, LING, DONG, FENGYUN, HOU, YINGLONG, CAI, WEIDONG, ZHOU, XIA, HUANG, AI-LING, YANG, MIN, ALLEN, THADDEUS D., LIU, JU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217775/
https://www.ncbi.nlm.nih.gov/pubmed/25371719
http://dx.doi.org/10.3892/etm.2014.1997