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Dihydroartemisinin inhibits vascular endothelial growth factor-induced endothelial cell migration by a p38 mitogen-activated protein kinase-independent pathway
Dihydroartemisinin (DHA), a semi-synthetic derivative of artemisinin, has been demonstrated to possess a strong antiangiogenic activity. However, the molecular mechanisms underlying this effect remain unclear. Endothelial cell (EC) migration is an essential component of angiogenesis, and the p38 mit...
Autores principales: | GUO, LING, DONG, FENGYUN, HOU, YINGLONG, CAI, WEIDONG, ZHOU, XIA, HUANG, AI-LING, YANG, MIN, ALLEN, THADDEUS D., LIU, JU |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217775/ https://www.ncbi.nlm.nih.gov/pubmed/25371719 http://dx.doi.org/10.3892/etm.2014.1997 |
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