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N-methyl-D-aspartate receptor antagonist MK-801 prevents apoptosis in rats that have undergone fetal spinal cord transplantation following spinal hemisection

Spinal cord injury is the main cause of paraplegia, but effective therapies for it are lacking. Embryonic spinal cord transplantation is able to repair spinal cord injury, albeit with a large amount of neuronal apoptosis remaining in the spinal cord. MK-801, an N-methyl-D-aspartate (NMDA) receptor a...

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Detalles Bibliográficos
Autores principales: ZHANG, QIANG, SHAO, YANG, ZHAO, CHANGSONG, CAI, JUAN, SUN, SHENG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218703/
https://www.ncbi.nlm.nih.gov/pubmed/25371724
http://dx.doi.org/10.3892/etm.2014.2029