Self-Propagative Replication of Aβ Oligomers Suggests Potential Transmissibility in Alzheimer Disease

The aggregation of amyloid-β (Aβ) peptide and its deposition in parts of the brain form the central processes in the etiology of Alzheimer disease (AD). The low-molecular weight oligomers of Aβ aggregates (2 to 30 mers) are known to be the primary neurotoxic agents whose mechanisms of cellular toxic...

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Detalles Bibliográficos
Autores principales: Kumar, Amit, Pate, Kayla M., Moss, Melissa A., Dean, Dexter N., Rangachari, Vijayaraghavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218758/
https://www.ncbi.nlm.nih.gov/pubmed/25365422
http://dx.doi.org/10.1371/journal.pone.0111492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218758/
https://www.ncbi.nlm.nih.gov/pubmed/25365422
http://dx.doi.org/10.1371/journal.pone.0111492

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