Sertraline Reduces IL-1β and TNF-α mRNA Expression and Overcomes Their Rise Induced by Seizures in the Rat Hippocampus

We recently discovered that the antidepressant sertraline is an effective inhibitor of hippocampus presynaptic Na(+) channel permeability in vitro and of tonic-clonic seizures in animals in vivo. Several studies indicate that the pro-inflammatory cytokines in the central nervous system are increased...

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Detalles Bibliográficos
Autores principales: Sitges, María, Gómez, Carlos D., Aldana, Blanca I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218797/
https://www.ncbi.nlm.nih.gov/pubmed/25364907
http://dx.doi.org/10.1371/journal.pone.0111665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218797/
https://www.ncbi.nlm.nih.gov/pubmed/25364907
http://dx.doi.org/10.1371/journal.pone.0111665

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