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Sertraline Reduces IL-1β and TNF-α mRNA Expression and Overcomes Their Rise Induced by Seizures in the Rat Hippocampus
We recently discovered that the antidepressant sertraline is an effective inhibitor of hippocampus presynaptic Na(+) channel permeability in vitro and of tonic-clonic seizures in animals in vivo. Several studies indicate that the pro-inflammatory cytokines in the central nervous system are increased...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218797/ https://www.ncbi.nlm.nih.gov/pubmed/25364907 http://dx.doi.org/10.1371/journal.pone.0111665 |