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Chronic Hypoxia Increases TRPC6 Expression and Basal Intracellular Ca(2+) Concentration in Rat Distal Pulmonary Venous Smooth Muscle

BACKGROUND: Hypoxia causes remodeling and contractile responses in both pulmonary artery (PA) and pulmonary vein (PV). Here we explore the effect of hypoxia on PV and pulmonary venous smooth muscle cells (PVSMCs). METHODS: Chronic hypoxic pulmonary hypertension (CHPH) model was established by exposi...

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Detalles Bibliográficos
Autores principales: Xu, Lei, Chen, Yuqin, Yang, Kai, Wang, Yingfeng, Tian, Lichun, Zhang, Jie, Wang, Elizabeth Wenqian, Sun, Dejun, Lu, Wenju, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218830/
https://www.ncbi.nlm.nih.gov/pubmed/25365342
http://dx.doi.org/10.1371/journal.pone.0112007