Generation of a Single Chain Antibody Variable Fragment (scFv) to Sense Selectively RhoB Activation

Determining the cellular level of activated form of RhoGTPases is of key importance to understand their regulatory functions in cell physiopathology. We previously reported scFvC1, that selectively bind to the GTP-bound form of RhoA, RhoB and RhoC. In this present study we generate, by molecular evo...

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Detalles Bibliográficos
Autores principales: Chinestra, Patrick, Olichon, Aurélien, Medale-Giamarchi, Claire, Lajoie-Mazenc, Isabelle, Gence, Rémi, Inard, Cyril, Ligat, Laetitia, Faye, Jean-Charles, Favre, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218836/
https://www.ncbi.nlm.nih.gov/pubmed/25365345
http://dx.doi.org/10.1371/journal.pone.0111034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218836/
https://www.ncbi.nlm.nih.gov/pubmed/25365345
http://dx.doi.org/10.1371/journal.pone.0111034

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