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The effects of ponatinib, a multi-targeted tyrosine kinase inhibitor, against human U87 malignant glioblastoma cells

Glioblastoma is one of the most common malignant tumors in the nervous system in both adult and pediatric patients. Studies suggest that abnormal activation of receptor tyrosine kinases contributes to pathological development of glioblastoma. However, current therapies targeting tyrosine kinase rece...

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Detalles Bibliográficos
Autores principales: Zhang, Junxia, Zhou, Qiang, Gao, Ge, Wang, Yanfen, Fang, Zhihui, Li, Guanlin, Yu, Mengfei, Kong, Lingfei, Xing, Ying, Gao, Xiaoqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218911/
https://www.ncbi.nlm.nih.gov/pubmed/25378936
http://dx.doi.org/10.2147/OTT.S67556