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Checkpoint-independent scaling of the Saccharomyces cerevisiae DNA replication program

BACKGROUND: In budding yeast, perturbations that prolong S phase lead to a proportionate delay in the activation times of most origins. The DNA replication checkpoint was implicated in this scaling phenotype, as an intact checkpoint was shown to be required for the delayed activation of late origins...

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Detalles Bibliográficos
Autores principales: Gispan, Ariel, Carmi, Miri, Barkai, Naama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218987/
https://www.ncbi.nlm.nih.gov/pubmed/25288172
http://dx.doi.org/10.1186/s12915-014-0079-z