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Stabilization of the β-hairpin in Mason-Pfizer monkey virus capsid protein– a critical step for infectivity

BACKGROUND: Formation of a mature core is a crucial event for infectivity of retroviruses such as Mason-Pfizer monkey virus (M-PMV). The process is triggered by proteolytic cleavage of the polyprotein precursor Gag, which releases matrix, capsid (CA), and nucleocapsid proteins. Once released, CA ass...

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Detalles Bibliográficos
Autores principales: Obr, Martin, Hadravová, Romana, Doležal, Michal, Křížová, Ivana, Papoušková, Veronika, Žídek, Lukáš, Hrabal, Richard, Ruml, Tomáš, Rumlová, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219007/
https://www.ncbi.nlm.nih.gov/pubmed/25365920
http://dx.doi.org/10.1186/s12977-014-0094-8