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A common gene expression signature in Huntington’s disease patient brain regions

BACKGROUND: Gene expression data provide invaluable insights into disease mechanisms. In Huntington’s disease (HD), a neurodegenerative disease caused by a tri-nucleotide repeat expansion in the huntingtin gene, extensive transcriptional dysregulation has been reported. Conventional dysregulation an...

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Detalles Bibliográficos
Autores principales: Neueder, Andreas, Bates, Gillian P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219025/
https://www.ncbi.nlm.nih.gov/pubmed/25358814
http://dx.doi.org/10.1186/s12920-014-0060-2