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Conditionally induced RAGE expression by proximal airway epithelial cells in transgenic mice causes lung inflammation

BACKGROUND: Receptors for advanced glycation end-products (RAGE) are multiligand cell-surface receptors expressed abundantly by distal pulmonary epithelium. Our lab has discovered RAGE-mediated effects in the orchestration of lung inflammation induced by tobacco smoke and environmental pollutants; h...

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Detalles Bibliográficos
Autores principales: Bodine, B Garrett, Bennion, Brock G, Leatham, Emma, Jimenez, Felix R, Wright, Alex J, Jergensen, Zac R, Erickson, Connor J, Jones, Cameron M, Johnson, Jeff P, Knapp, Steven M, Reynolds, Paul R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219035/
https://www.ncbi.nlm.nih.gov/pubmed/25359169
http://dx.doi.org/10.1186/s12931-014-0133-y