The cn/cn dwarf mouse. Histomorphometric, ultrastructural, and radiographic study in mutants corresponding to human acromesomelic dysplasia Maroteaux type (AMDM)

BACKGROUND: The cn/cn dwarf mouse is caused by a loss-of-function mutation in the natriuretic peptide receptor 2 (NPR-2) gene which helps positively regulate endochondral longitudinal bone growth. The gene mutation corresponds to that in the human skeletal dysplasia Acromesomelic Dysplasia Maroteaux...

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Detalles Bibliográficos
Autores principales: Shapiro, Frederic, Barone, Lauren, Johnson, Andrew, Flynn, Evelyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219045/
https://www.ncbi.nlm.nih.gov/pubmed/25319082
http://dx.doi.org/10.1186/1471-2474-15-347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219045/
https://www.ncbi.nlm.nih.gov/pubmed/25319082
http://dx.doi.org/10.1186/1471-2474-15-347

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