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MAR-mediated integration of plasmid vectors for in vivo gene transfer and regulation

BACKGROUND: The in vivo transfer of naked plasmid DNA into organs such as muscles is commonly used to assess the expression of prophylactic or therapeutic genes in animal disease models. RESULTS: In this study, we devised vectors allowing a tight regulation of transgene expression in mice from such...

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Detalles Bibliográficos
Autores principales: Puttini, Stefania, van Zwieten, Ruthger W, Saugy, Damien, Lekka, Małgorzata, Hogger, Florence, Ley, Deborah, Kulik, Andrzej J, Mermod, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219123/
https://www.ncbi.nlm.nih.gov/pubmed/24295286
http://dx.doi.org/10.1186/1471-2199-14-26