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Risk of bias: a simulation study of power to detect study-level moderator effects in meta-analysis

BACKGROUND: There are both theoretical and empirical reasons to believe that design and execution factors are associated with bias in controlled trials. Statistically significant moderator effects, such as the effect of trial quality on treatment effect sizes, are rarely detected in individual meta-...

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Detalles Bibliográficos
Autores principales: Hempel, Susanne, Miles, Jeremy NV, Booth, Marika J, Wang, Zhen, Morton, Sally C, Shekelle, Paul G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219184/
https://www.ncbi.nlm.nih.gov/pubmed/24286208
http://dx.doi.org/10.1186/2046-4053-2-107