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Genetic polymorphism in the NRF2 gene as a prognosis marker for cancer chemotherapy

NF-E2-related factor 2 (NRF2) is a transcription factor that controls the expression of a variety of antioxidant and detoxification genes. Accumulating evidence strongly suggests that NRF2 mediates cancer cell proliferation and drug resistance, as well. Single nucleotide polymorphism (SNP) -617C >...

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Detalles Bibliográficos
Autor principal: Ishikawa, Toshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219421/
https://www.ncbi.nlm.nih.gov/pubmed/25408701
http://dx.doi.org/10.3389/fgene.2014.00383