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Genetic polymorphism in the NRF2 gene as a prognosis marker for cancer chemotherapy
NF-E2-related factor 2 (NRF2) is a transcription factor that controls the expression of a variety of antioxidant and detoxification genes. Accumulating evidence strongly suggests that NRF2 mediates cancer cell proliferation and drug resistance, as well. Single nucleotide polymorphism (SNP) -617C >...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219421/ https://www.ncbi.nlm.nih.gov/pubmed/25408701 http://dx.doi.org/10.3389/fgene.2014.00383 |