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A pre-clinical model of resistance to induction therapy in pediatric acute lymphoblastic leukemia
Relapse and acquired drug resistance in T-cell acute lymphoblastic leukemia (T-ALL) remains a significant clinical problem. This study was designed to establish a preclinical model of resistance to induction therapy in childhood T-ALL to examine the emergence of drug resistance and identify novel th...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219466/ https://www.ncbi.nlm.nih.gov/pubmed/25083816 http://dx.doi.org/10.1038/bcj.2014.52 |