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A pre-clinical model of resistance to induction therapy in pediatric acute lymphoblastic leukemia

Relapse and acquired drug resistance in T-cell acute lymphoblastic leukemia (T-ALL) remains a significant clinical problem. This study was designed to establish a preclinical model of resistance to induction therapy in childhood T-ALL to examine the emergence of drug resistance and identify novel th...

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Detalles Bibliográficos
Autores principales: Samuels, A L, Beesley, A H, Yadav, B D, Papa, R A, Sutton, R, Anderson, D, Marshall, G M, Cole, C H, Kees, U R, Lock, R B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219466/
https://www.ncbi.nlm.nih.gov/pubmed/25083816
http://dx.doi.org/10.1038/bcj.2014.52