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Breast cancers with high DSS1 expression that potentially maintains BRCA2 stability have poor prognosis in the relapse-free survival

BACKGROUND: Genetic BRCA2 insufficiency is associated with breast cancer development; however, in sporadic breast cancer cases, high BRCA2 expression is paradoxically correlated with poor prognosis. Because DSS1, a mammalian component of the transcription/RNA export complex, is known to stabilize BR...

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Detalles Bibliográficos
Autores principales: Rezano, Andri, Kuwahara, Kazuhiko, Yamamoto-Ibusuki, Mutsuko, Kitabatake, Masahiro, Moolthiya, Penpak, Phimsen, Suchada, Suda, Taiji, Tone, Shigenobu, Yamamoto, Yutaka, Iwase, Hirotaka, Sakaguchi, Nobuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219476/
https://www.ncbi.nlm.nih.gov/pubmed/24289229
http://dx.doi.org/10.1186/1471-2407-13-562