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Breast cancers with high DSS1 expression that potentially maintains BRCA2 stability have poor prognosis in the relapse-free survival
BACKGROUND: Genetic BRCA2 insufficiency is associated with breast cancer development; however, in sporadic breast cancer cases, high BRCA2 expression is paradoxically correlated with poor prognosis. Because DSS1, a mammalian component of the transcription/RNA export complex, is known to stabilize BR...
Autores principales: | Rezano, Andri, Kuwahara, Kazuhiko, Yamamoto-Ibusuki, Mutsuko, Kitabatake, Masahiro, Moolthiya, Penpak, Phimsen, Suchada, Suda, Taiji, Tone, Shigenobu, Yamamoto, Yutaka, Iwase, Hirotaka, Sakaguchi, Nobuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219476/ https://www.ncbi.nlm.nih.gov/pubmed/24289229 http://dx.doi.org/10.1186/1471-2407-13-562 |
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