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Inhibition of NKCC1 Attenuated Hippocampal LTP Formation and Inhibitory Avoidance in Rat

The loop diuretic bumetanide (Bumex) is thought to have antiepileptic properties via modulate GABA(A) mediated signaling through their antagonism of cation-chloride cotransporters. Given that loop diuretics may act as antiepileptic drugs that modulate GABAergic signaling, we sought to investigate wh...

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Detalles Bibliográficos
Autores principales: Ko, Meng Chang, Lee, Min Chong, Amstislavskaya, Tamara G., Tikhonova, Maria A., Yang, Yi-Ling, Lu, Kwok-Tung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219661/
https://www.ncbi.nlm.nih.gov/pubmed/25369049
http://dx.doi.org/10.1371/journal.pone.0106692