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Protection of Armadillo/β-Catenin by Armless, a Novel Positive Regulator of Wingless Signaling
The Wingless (Wg/Wnt) signaling pathway is essential for metazoan development, where it is central to tissue growth and cellular differentiation. Deregulated Wg pathway activation underlies severe developmental abnormalities, as well as carcinogenesis. Armadillo/β-Catenin plays a key role in the Wg...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219662/ https://www.ncbi.nlm.nih.gov/pubmed/25369031 http://dx.doi.org/10.1371/journal.pbio.1001988 |