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GTP Cyclohydrolase I Gene Polymorphisms Are Associated with Endothelial Dysfunction and Oxidative Stress in Patients with Type 2 Diabetes Mellitus

BACKGROUND: The genetic background of atherosclerosis in type 2 diabetes mellitus (T2DM) is complex and poorly understood. Studying genetic components of intermediate phenotypes, such as endothelial dysfunction and oxidative stress, may aid in identifying novel genetic components for atherosclerosis...

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Detalles Bibliográficos
Autores principales: Wolkow, Pawel P., Kosiniak-Kamysz, Wladyslaw, Osmenda, Grzegorz, Wilk, Grzegorz, Bujak-Gizycka, Beata, Ignacak, Adam, Kanitkar, Mihir, Walus-Miarka, Malgorzata, Harrison, David G., Korbut, Ryszard, Malecki, Maciej T., Guzik, Tomasz J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219671/
https://www.ncbi.nlm.nih.gov/pubmed/25369080
http://dx.doi.org/10.1371/journal.pone.0108587